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Interleukin-18 receptor

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Immunopharmacology Ligand  Target has curated data in GtoImmuPdb

Target id: 1908

Nomenclature: Interleukin-18 receptor

Family: Immunoglobulin-like family of IL-1 receptors

Quaternary Structure: Subunits
Interleukin-18 receptor 1 (Ligand-binding subunit)
IL-18 receptor accessory protein (Other subunit)
Natural/Endogenous Ligands Click here for help
IL-18 {Sp: Human}
IL-37 {Sp: Human}

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Agonists
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Ligand Sp. Action Value Parameter Reference
IL-18 {Sp: Human} Peptide Ligand is endogenous in the given species Immunopharmacology Ligand Hs Agonist - -
IL-37 {Sp: Human} Peptide Click here for species-specific activity table Ligand is endogenous in the given species Immunopharmacology Ligand Hs Agonist - -
Immunopharmacology Comments
The functional IL-18 receptor is a heterodimer containing the interleukin-18 1 protein (IL18R1) as the ligand binding moeity, and the IL-18 receptor accessory protein (IL18RAP).

How to cite this page

Immunoglobulin-like family of IL-1 receptors: Interleukin-18 receptor. Last modified on 22/03/2017. Accessed on 05/10/2022. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetoimmunopharmacology.org/GRAC/ObjectDisplayForward?objectId=1908.