Top ▲
GtoPdb is requesting financial support from commercial users. Please see our sustainability page for more information.
                                        
  Target has curated data in GtoImmuPdb
                                        
                                        
                                        
                                        
                   
                                
                                
                            
                            
                            
                                
                        
Target id: 1737
Nomenclature: Interleukin-18 receptor 1
| Quaternary Structure: Complexes | 
| Interleukin-18 receptor | 
Gene and Protein Information ![]()  | 
                                    ||||||
| Species | TM | AA | Chromosomal Location | Gene Symbol | Gene Name | Reference | 
| Human | 1 | 541 | 2q12.1 | IL18R1 | interleukin 18 receptor 1 | |
| Mouse | 1 | 537 | 1 B | Il18r1 | interleukin 18 receptor 1 | |
| Rat | - | - | Il18r1 | interleukin 18 receptor 1 | ||
Previous and Unofficial Names ![]()  | 
                                
| CD218a | Il18ralpha | IL1RRP | interleukin 18 receptor 1 | 
Database Links ![]()  | 
                            |
| Alphafold | Q13478 (Hs), Q61098 (Mm) | 
| CATH/Gene3D | 2.60.40.10, 3.40.50.10140 | 
| ChEMBL Target | CHEMBL4804253 (Hs) | 
| Ensembl Gene | ENSG00000115604 (Hs), ENSMUSG00000026070 (Mm), ENSRNOG00000015027 (Rn) | 
| Entrez Gene | 8809 (Hs), 16182 (Mm), 301365 (Rn) | 
| Human Protein Atlas | ENSG00000115604 (Hs) | 
| KEGG Gene | hsa:8809 (Hs), mmu:16182 (Mm), rno:301365 (Rn) | 
| OMIM | 604494 (Hs) | 
| Pharos | Q13478 (Hs) | 
| UniProtKB | Q13478 (Hs), Q61098 (Mm) | 
| Wikipedia | IL18R1 (Hs) | 
| Immunopharmacology Comments | 
| Interleukin-18 1 protein (IL18R1) is the ligand binding subunit of the functional IL-18 receptor heterodimer. | 
Immunoglobulin-like family of IL-1 receptors: Interleukin-18 receptor 1. Last modified on 30/10/2017. Accessed on 04/11/2025. IUPHAR/BPS Guide to PHARMACOLOGY, https://www.guidetoimmunopharmacology.org/GRAC/ObjectDisplayForward?objectId=1737.