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Target has curated data in GtoImmuPdb
Target id: 1737
Nomenclature: Interleukin-18 receptor 1
Quaternary Structure: Complexes |
Interleukin-18 receptor |
Gene and Protein Information | ||||||
Species | TM | AA | Chromosomal Location | Gene Symbol | Gene Name | Reference |
Human | 1 | 541 | 2q12.1 | IL18R1 | interleukin 18 receptor 1 | |
Mouse | 1 | 537 | 1 B | Il18r1 | interleukin 18 receptor 1 | |
Rat | - | - | Il18r1 | interleukin 18 receptor 1 |
Previous and Unofficial Names |
CD218a | Il18ralpha | IL1RRP | interleukin 18 receptor 1 |
Database Links | |
Alphafold | Q13478 (Hs), Q61098 (Mm) |
CATH/Gene3D | 2.60.40.10, 3.40.50.10140 |
ChEMBL Target | CHEMBL4804253 (Hs) |
Ensembl Gene | ENSG00000115604 (Hs), ENSMUSG00000026070 (Mm), ENSRNOG00000015027 (Rn) |
Entrez Gene | 8809 (Hs), 16182 (Mm), 301365 (Rn) |
Human Protein Atlas | ENSG00000115604 (Hs) |
KEGG Gene | hsa:8809 (Hs), mmu:16182 (Mm), rno:301365 (Rn) |
OMIM | 604494 (Hs) |
Pharos | Q13478 (Hs) |
UniProtKB | Q13478 (Hs), Q61098 (Mm) |
Wikipedia | IL18R1 (Hs) |
Immunopharmacology Comments |
Interleukin-18 1 protein (IL18R1) is the ligand binding subunit of the functional IL-18 receptor heterodimer. |
Immuno Process Associations | ||
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Immunoglobulin-like family of IL-1 receptors: Interleukin-18 receptor 1. Last modified on 30/10/2017. Accessed on 07/11/2024. IUPHAR/BPS Guide to PHARMACOLOGY, https://www.guidetoimmunopharmacology.org/GRAC/ObjectDisplayForward?objectId=1737.