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Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).
The immunoglobulin-like family of IL-1 receptors are heterodimeric receptors made up of a cognate receptor subunit and an IL-1 receptor accessory protein, IL1RAP (Q9NPH3, also known as C3orf13, IL-1RAcP, IL1R3). They are characterised by extracellular immunoglobulin-like domains and an intracellular Toll/Interleukin-1R (TIR) domain.
Interleukin-1 receptor, type I C Show summary » More detailed page |
Interleukin-33 receptor C Show summary » More detailed page |
Interleukin-36 receptor C Show summary » More detailed page |
Interleukin-1 receptor, type II C Show summary » More detailed page |
Interleukin-18 receptor C Show summary » More detailed page |
Interleukin 1 receptor, type I C Show summary » More detailed page |
Interleukin 1 receptor, type II C Show summary » More detailed page |
Interleukin-1 receptor-like 1 C Show summary » More detailed page |
Interleukin-1 receptor-like 2 C Show summary » More detailed page |
Interleukin-18 receptor 1 C Show summary » More detailed page |
single Ig and TIR domain containing / IL-1R8 Show summary » More detailed page |
IL-1 receptor accessory protein Show summary » More detailed page |
IL-18 receptor accessory protein Show summary » More detailed page |
Database page citation:
Immunoglobulin-like family of IL-1 receptors. Accessed on 10/12/2024. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=312.
Concise Guide to PHARMACOLOGY citation:
Alexander SPH, Fabbro D, Kelly E, Mathie AA, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Davies JA et al. (2023) The Concise Guide to PHARMACOLOGY 2023/24: Catalytic receptors. Br J Pharmacol. 180 Suppl 2:S241-288.