fenfluramine   Click here for help

GtoPdb Ligand ID: 4613

Synonyms: Adifax® | Fintepla® | Pondimin® | ZX008
Approved drug
fenfluramine is an approved drug (FDA (2020))
Compound class: Synthetic organic
Comment: The approved drug was called dexfenfluramine, but was withdrawn from use due to adverse cardiac events [1,3].
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2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 1
Hydrogen bond donors 1
Rotatable bonds 5
Topological polar surface area 12.03
Molecular weight 231.12
XLogP 3.5
No. Lipinski's rules broken 0
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Canonical SMILES CCNC(Cc1cccc(c1)C(F)(F)F)C
Isomeric SMILES CCNC(Cc1cccc(c1)C(F)(F)F)C
InChI InChI=1S/C12H16F3N/c1-3-16-9(2)7-10-5-4-6-11(8-10)12(13,14)15/h4-6,8-9,16H,3,7H2,1-2H3
Classification Click here for help
Compound class Synthetic organic
Approved drug? Yes (FDA (2020))
IUPAC Name Click here for help
International Nonproprietary Names Click here for help
INN number INN
5818 dexfenfluramine
1596 fenfluramine
Synonyms Click here for help
Adifax® | Fintepla® | Pondimin® | ZX008
Database Links Click here for help
CAS Registry No. 458-24-2 (source: Scifinder)
ChEMBL Ligand CHEMBL87493
DrugBank Ligand DB01191
DrugCentral Ligand 1150
GtoPdb PubChem SID 178101333
PubChem CID 3337
Search Google for chemical match using the InChIKey DBGIVFWFUFKIQN-UHFFFAOYSA-N
Search Google for chemicals with the same backbone DBGIVFWFUFKIQN
Search PubMed clinical trials fenfluramine
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UniChem Compound Search for chemical match using the InChIKey DBGIVFWFUFKIQN-UHFFFAOYSA-N
UniChem Connectivity Search for chemical match using the InChIKey DBGIVFWFUFKIQN-UHFFFAOYSA-N
Wikipedia Fenfluramine