blonanserin   Click here for help

GtoPdb Ligand ID: 7670

Synonyms: AD 5423 | AD-5423 | Lonasen®
Approved drug
blonanserin is an approved drug
Compound class: Synthetic organic
Comment: Blonanserin is an atypical antipsychotic.
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2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 3
Topological polar surface area 19.37
Molecular weight 367.24
XLogP 6.05
No. Lipinski's rules broken 1
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Canonical SMILES CCN1CCN(CC1)c1nc2CCCCCCc2c(c1)c1ccc(cc1)F
Isomeric SMILES CCN1CCN(CC1)c1nc2CCCCCCc2c(c1)c1ccc(cc1)F
InChI InChI=1S/C23H30FN3/c1-2-26-13-15-27(16-14-26)23-17-21(18-9-11-19(24)12-10-18)20-7-5-3-4-6-8-22(20)25-23/h9-12,17H,2-8,13-16H2,1H3
1. Ochi T, Sakamoto M, Minamida A, Suzuki K, Ueda T, Une T, Toda H, Matsumoto K, Terauchi Y. (2005)
Syntheses and properties of the major hydroxy metabolites in humans of blonanserin AD-5423, a novel antipsychotic agent.
Bioorg Med Chem Lett, 15 (4): 1055-9. [PMID:15686911]
2. Oka M, Noda Y, Ochi Y, Furukawa K, Une T, Kurumiya S, Hino K, Karasawa T. (1993)
Pharmacological profile of AD-5423, a novel antipsychotic with both potent dopamine-D2 and serotonin-S2 antagonist properties.
J Pharmacol Exp Ther, 264 (1): 158-65. [PMID:8093723]