blonanserin [Ligand Id: 7670] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL178803 (AD-5423, Blonanserin, DSP-5423) |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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| D2 receptor/Dopamine D2 receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL217] [GtoPdb: 215] [UniProtKB: P14416] | ||||||||
| GtoPdb | - | - | 9.85 | pKi | 0.14 | nM | Ki | Bioorg Med Chem Lett (2005) 15: 1055-9 [PMID:15686911] |
| ChEMBL | In vitro binding affinity against recombinant human dopamine receptor D2L in human liver microsomes | B | 9.85 | pKi | 0.14 | nM | Ki | Bioorg Med Chem Lett (2005) 15: 1055-1059 [PMID:15686911] |
| 5-HT2A receptor/Serotonin 2a (5-HT2a) receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL224] [GtoPdb: 6] [UniProtKB: P28223] | ||||||||
| GtoPdb | - | - | 9.09 | pKi | 0.81 | nM | Ki | Bioorg Med Chem Lett (2005) 15: 1055-9 [PMID:15686911] |
| ChEMBL | In vitro binding affinity against recombinant human 5-hydroxytryptamine 2A receptor in human liver microsomes | B | 9.09 | pKi | 0.81 | nM | Ki | Bioorg Med Chem Lett (2005) 15: 1055-1059 [PMID:15686911] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
