growth/differentiation factor-6

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Ligands
growth/differentiation factor-6 (Human)

GtoPdb Ligand ID: 4878

Abbreviated name: GDF6

Synonyms: BMP13 | bone morphogenetic protein 13 | GDF-6 | growth/differentiation factor 16

Compound class: Endogenous peptide in human, mouse or rat

Comment: The active peptide is a disulphide bond-linked homodimer. May signal through BMPR1A, BMPR1B, BMPR2 and ActR2 [1].

Species: Human

Summary
Biological activity
References
Structure
Similar ligands

References
1. Asai-Coakwell M, March L, Dai XH, Duval M, Lopez I, French CR, Famulski J, De Baere E, Francis PJ, Sundaresan P et al.. (2013) Contribution of growth differentiation factor 6-dependent cell survival to early-onset retinal dystrophies. Hum Mol Genet, 22 (7): 1432-42. [PMID:23307924]

References

1. Asai-Coakwell M, March L, Dai XH, Duval M, Lopez I, French CR, Famulski J, De Baere E, Francis PJ, Sundaresan P et al.. (2013)
Contribution of growth differentiation factor 6-dependent cell survival to early-onset retinal dystrophies.
Hum Mol Genet, 22 (7): 1432-42. [PMID:23307924]