furosemide

Ligand id: 4839

Name: furosemide

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Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 3
Rotatable bonds 5
Topological polar surface area 131.01
Molecular weight 330.01
XLogP 1.2
No. Lipinski's rules broken 0

Molecular properties generated using the CDK
References
1. Hannaert P, Alvarez-Guerra M, Pirot D, Nazaret C, Garay RP. (2002)
Rat NKCC2/NKCC1 cotransporter selectivity for loop diuretic drugs.
Naunyn Schmiedebergs Arch. Pharmacol., 365 (3): 193-9. [PMID:11882915]
2. Yang Y, Fu A, Wu X, Reagan JD. (2012)
GPR35 is a target of the loop diuretic drugs bumetanide and furosemide.
Pharmacology, 89 (1-2): 13-7. [PMID:22236570]