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MCS110   Click here for help

GtoPdb Ligand ID: 9110

Immunopharmacology Ligand
Compound class: Antibody
Comment: MCS110 is a myeloid cell targeting agent, specifically an IgG1 kappa monoclonal antibody against the ligand CSF-1 (a.k.a. M-CSF). It is being investigated for its immuno-oncology potential. This is one of the antibody constructs claimed in patent WO2007016240 [1].
Immunopharmacology Comments
MCS110 is a CSF1R signalling inhibitor that acts by sequestering CSF-1 ligand. It is included in GtoImmuPdb as a novel immuno-oncology agent.