CXCL16   Click here for help

GtoPdb Ligand ID: 855

Immunopharmacology Ligand
Comment: CXC chemokine ligand (CXCL) 16 is a ligand for chemokine receptor CXCR6. Once cleaved from the cell membrane CXCL16 acts as a chemoattractant for activated CD8 T cells, NKT cells and Th1-polarized T cells that express CXCR6.
Species: Human
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Immunopharmacology Comments
CXCL16 expression has been studied mainly in macrophages and dendritic cells, but evidence suggests expression in non-immune cells with suggested roles in epidermal immune surveillance and response to pathogens [1].