CXCL11   Click here for help

GtoPdb Ligand ID: 836

Synonyms: IP9 | ITAC
Immunopharmacology Ligand
Comment: CXCL11 is a C-X-C motif chemokine. It exerts its biological effects via interaction with the CXCR3 GPCR.
Species: Human
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Immunopharmacology Comments
CXCL11 expression is induced by interferons γ, β and to a lesser extent by INF-α. It acts as a chemoattractant for activated T cells.
Immunopharmacology Disease
Disease X-Refs Comment References
Psoriasis Disease Ontology: DOID:8893
CXCL11 (and CCL5) expression is increased in lesional compared with nonlesional psoriatic skin, and levels correlate with levels of IFNγ in the skin samples. 2