CXCL11   Click here for help

GtoPdb Ligand ID: 836

Synonyms: IP9 | ITAC
Immunopharmacology Ligand
Comment: CXCL11 is a C-X-C motif chemokine. It exerts its biological effects via interaction with the CXCR3 GPCR.
Species: Human
Click here for help
1. Heise CE, Pahuja A, Hudson SC, Mistry MS, Putnam AL, Gross MM, Gottlieb PA, Wade WS, Kiankarimi M, Schwarz D et al.. (2005)
Pharmacological characterization of CXC chemokine receptor 3 ligands and a small molecule antagonist.
J Pharmacol Exp Ther, 313 (3): 1263-71. [PMID:15761110]
2. Johansen C, Rittig AH, Mose M, Bertelsen T, Weimar I, Nielsen J, Andersen T, Rasmussen TK, Deleuran B, Iversen L. (2017)
STAT2 is involved in the pathogenesis of psoriasis by promoting CXCL11 and CCL5 production by keratinocytes.
PLoS ONE, 12 (5): e0176994. [PMID:28472186]