Ligand id: 7157

Name: desloratadine

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 0
Topological polar surface area 24.92
Molecular weight 310.12
XLogP 3.19
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Desloratadine is used to treat the symptoms (eg rhinitis and urticaria) of many allergic conditions. In some countries this drug is available without prescription.
Mechanism Of Action and Pharmacodynamic Effects
Desloratadine blocks the action of endogenous histamine at the histamine H1 receptor.
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