Ligand id: 7157

Name: desloratadine

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 0
Topological polar surface area 24.92
Molecular weight 310.12
XLogP 3.19
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

1. Lewis TA, Young MA, Arrington MP, Bayless L, Cai X, Collart P, Eckman JB, Ellis JL, Ene DG, Libertine L et al.. (2004)
Cetirizine and loratadine-based antihistamines with 5-lipoxygenase inhibitory activity.
Bioorg. Med. Chem. Lett., 14 (22): 5591-4. [PMID:15482930]