|Doxycycline is used to treat a wide range of bacterial infections. These include acne, urinary tract infections, intestinal infections, eye infections, gonorrhea, chlamydia, periodontitis (gum disease), lesions caused by rosacea, anthrax, and to treat infections resulting from by mite, tick, or lice infestations.
It is also used to prevent malaria (particularly useful in areas where chloroquine or multidrug-resistant P. falciparum are found) and as an effective treatment for severe malaria, when used as a combination therapy . It should not be used as a monotherapy for malaria treatment due to a delayed antimalarial effect (see MOA for more details).
Marketed formulations may contain doxycycline hyclate or doxycycline monohydrate.