procaterol   Click here for help

GtoPdb Ligand ID: 3464

Approved drug Immunopharmacology Ligand
procaterol is an approved drug
Compound class: Synthetic organic
Comment: The approved drug procaterol is a mixture of 1R 2S and 1S, 2R stereoisomers. Four isomers are listed by PubChem.
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2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 3
Hydrogen bond donors 4
Rotatable bonds 5
Topological polar surface area 85.35
Molecular weight 290.16
XLogP 2.8
No. Lipinski's rules broken 0
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Canonical SMILES CCC(C(c1ccc(c2c1ccc(=O)[nH]2)O)O)NC(C)C
Isomeric SMILES CCC(C(c1ccc(c2c1ccc(=O)[nH]2)O)O)NC(C)C
InChI InChI=1S/C16H22N2O3/c1-4-12(17-9(2)3)16(21)11-5-7-13(19)15-10(11)6-8-14(20)18-15/h5-9,12,16-17,19,21H,4H2,1-3H3,(H,18,20)
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Summary of Clinical Use Click here for help
Used in the treatment of asthma and chronic obstructive pulmonary disease. However, there is no information regarding approval for use of this drug on the US FDA or European Medicines Agency websites, although the compound does have an INN. Other national approval agencies may have granted marketing authorisation. See's International Drug Names list for futher information.
Mechanism Of Action and Pharmacodynamic Effects Click here for help
Agonism of β2-adrenoceptors in the lung causes bronchial smooth muscle relaxation, bronchodilation and increased bronchial airflow.