tositumomab   Click here for help

GtoPdb Ligand ID: 6781

Synonyms: Bexxar® | V10XA53
Approved drug Immunopharmacology Ligand
tositumomab is an approved drug (FDA (2003))
Compound class: Antibody
Comment: Tositumomab was used as a radioimmunotherapy drug, targeting CD20 on B-lymphocytes prior to cessation of its manufacture.
Bioactivity Comments
We have been unable to find any publicly available affinity value for the interaction between tositumomab and its antigen, CD20. The patent covering the use of radioactively-labelled anti-CD20 antibodies [2] refers back to articles and abstracts published in the early 1980's [1,3], none of which provide affinity data.
Selectivity at other protein targets
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
CD20 (membrane-spanning 4-domains, subfamily A, member 1) Primary target of this compound Hs Antibody Binding - - -