norrin   Click here for help

GtoPdb Ligand ID: 2947

Comment: Norrin: is the protein product of the Norrie disease gene NDP, is a secreted protein whose biochemical function is not yet fully understood. This protein is highly homologous to the human sequence and is conserved in rat.
Species: Mouse
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Natural/Endogenous Targets
Selectivity at GPCRs
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
FZD4 Ligand is endogenous in the given species Mm Agonist Full agonist 8.4 pKd - 1
pKd 8.4 [1]