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elafin   Click here for help

GtoPdb Ligand ID: 12035

Synonyms: cementoin | trappin-2
Immunopharmacology Ligand
Compound class: Endogenous peptide in human, mouse or rat
Comment: Elafin is a protease inhibitor and it is an endogenous antimicrobial peptide. It is a component of the innate immune response and contributes to controlling microbial infection in mucosal surfaces [1,3-6]. Therapeutic potential of elafin and its precursor trappin-2 is discussed by Deraison et al. (2022) [2].
Species: Human
Classification Click here for help
Compound class Endogenous peptide in human, mouse or rat
Synonyms Click here for help
cementoin | trappin-2
Gene/Precursor Click here for help
Gene symbol Gene name Species Precursor protein name Synonyms
PI3 peptidase inhibitor 3 Human elafin precursor, Skin-derived antileukoproteinase (SKALP)
Database Links Click here for help
Ensembl Gene ENSG00000124102 (Hs)
Entrez Gene 5266 (Hs)
GtoPdb PubChem SID 464244176
Human Protein Atlas ENSG00000124102 (Hs)
OMIM 182257 (Hs)
UniProtKB P19957 (Hs)