sitravatinib [Ligand Id: 9920] activity data from GtoPdb
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| platelet derived growth factor receptor alpha in Human [GtoPdb: 1803] [UniProtKB: P16234] | ||||||||
| GtoPdb | In a biochemical enzyme activity assay. | - | 7.52 | pIC50 | 30 | nM | IC50 | Oncotarget (2016) 7: 4093-109 [PMID:26675259] |
| KIT proto-oncogene, receptor tyrosine kinase in Human [GtoPdb: 1805] [UniProtKB: P10721] | ||||||||
| GtoPdb | In a biochemical enzyme activity assay. | - | 8.22 | pIC50 | 6 | nM | IC50 | Oncotarget (2016) 7: 4093-109 [PMID:26675259] |
| fms related receptor tyrosine kinase 3 in Human [GtoPdb: 1807] [UniProtKB: P36888] | ||||||||
| GtoPdb | In a biochemical enzyme activity assay. | - | 8.1 | pIC50 | 8 | nM | IC50 | Oncotarget (2016) 7: 4093-109 [PMID:26675259] |
| fms related receptor tyrosine kinase 1 in Human [GtoPdb: 1812] [UniProtKB: P17948] | ||||||||
| GtoPdb | In a biochemical enzyme activity assay. | - | 8.22 | pIC50 | 6 | nM | IC50 | Oncotarget (2016) 7: 4093-109 [PMID:26675259] |
| kinase insert domain receptor in Human [GtoPdb: 1813] [UniProtKB: P35968] | ||||||||
| GtoPdb | In a biochemical enzyme activity assay. | - | 8.3 | pIC50 | 5 | nM | IC50 | Oncotarget (2016) 7: 4093-109 [PMID:26675259] |
| fms related receptor tyrosine kinase 4 in Human [GtoPdb: 1814] [UniProtKB: P35916] | ||||||||
| GtoPdb | In a biochemical enzyme activity assay. | - | 8.7 | pIC50 | 2 | nM | IC50 | Oncotarget (2016) 7: 4093-109 [PMID:26675259] |
| MET proto-oncogene, receptor tyrosine kinase in Human [GtoPdb: 1815] [UniProtKB: P08581] | ||||||||
| GtoPdb | In a biochemical enzyme activity assay. | - | 7.7 | pIC50 | 20 | nM | IC50 | Oncotarget (2016) 7: 4093-109 [PMID:26675259] |
| neurotrophic receptor tyrosine kinase 1 in Human [GtoPdb: 1817] [UniProtKB: P04629] | ||||||||
| GtoPdb | In a biochemical enzyme activity assay. | - | 8.3 | pIC50 | 5 | nM | IC50 | Oncotarget (2016) 7: 4093-109 [PMID:26675259] |
| EPH receptor A3 in Human [GtoPdb: 1823] [UniProtKB: P29320] | ||||||||
| GtoPdb | In a biochemical enzyme activity assay. | - | 9 | pIC50 | 1 | nM | IC50 | Oncotarget (2016) 7: 4093-109 [PMID:26675259] |
| AXL receptor tyrosine kinase in Human [GtoPdb: 1835] [UniProtKB: P30530] | ||||||||
| GtoPdb | In a biochemical enzyme activity assay. | - | 8.82 | pIC50 | 1.5 | nM | IC50 | Oncotarget (2016) 7: 4093-109 [PMID:26675259] |
| MER proto-oncogene, tyrosine kinase in Human [GtoPdb: 1837] [UniProtKB: Q12866] | ||||||||
| GtoPdb | In a biochemical enzyme activity assay. | - | 8.7 | pIC50 | 2 | nM | IC50 | Oncotarget (2016) 7: 4093-109 [PMID:26675259] |
| discoidin domain receptor tyrosine kinase 2 in Human [GtoPdb: 1844] [UniProtKB: Q16832] | ||||||||
| GtoPdb | In a biochemical enzyme activity assay. | - | 9.3 | pIC50 | 0.5 | nM | IC50 | Oncotarget (2016) 7: 4093-109 [PMID:26675259] |
Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.
