ChEMBL ligand: CHEMBL1784637
platelet derived growth factor receptor alpha in Human [GtoPdb: 1803] [UniProtKB: P16234] There should be some charts here, you may need to enable JavaScript!
EPH receptor A2 in Human [GtoPdb: 1822] [UniProtKB: P29317] There should be some charts here, you may need to enable JavaScript!
EPH receptor A3 in Human [GtoPdb: 1823] [UniProtKB: P29320] There should be some charts here, you may need to enable JavaScript!
EPH receptor A7 in Human [GtoPdb: 1827] [UniProtKB: Q15375] There should be some charts here, you may need to enable JavaScript!
TEK receptor tyrosine kinase in Human [GtoPdb: 1842] [UniProtKB: Q02763] There should be some charts here, you may need to enable JavaScript!
ABL proto-oncogene 1, non-receptor tyrosine kinase in Human [GtoPdb: 1923] [UniProtKB: P00519] There should be some charts here, you may need to enable JavaScript!
ret proto-oncogene in Human [GtoPdb: 2185] [UniProtKB: P07949] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
platelet derived growth factor receptor alpha in Human [GtoPdb: 1803] [UniProtKB: P16234]
GtoPdb	-	-	8.89	pIC50	1.3	nM	IC50	Bioorg Med Chem Lett (2011) 21: 3743-8 [PMID:21561767]
EPH receptor A2 in Human [GtoPdb: 1822] [UniProtKB: P29317]
GtoPdb	-	-	9.22	pIC50	0.6	nM	IC50	Bioorg Med Chem Lett (2011) 21: 3743-8 [PMID:21561767]
EPH receptor A3 in Human [GtoPdb: 1823] [UniProtKB: P29320]
GtoPdb	-	-	8.92	pIC50	1.2	nM	IC50	Bioorg Med Chem Lett (2011) 21: 3743-8 [PMID:21561767]
EPH receptor A7 in Human [GtoPdb: 1827] [UniProtKB: Q15375]
GtoPdb	-	-	8.38	pIC50	4.2	nM	IC50	Bioorg Med Chem Lett (2011) 21: 3743-8 [PMID:21561767]
TEK receptor tyrosine kinase in Human [GtoPdb: 1842] [UniProtKB: Q02763]
GtoPdb	-	-	8.66	pIC50	2.2	nM	IC50	Bioorg Med Chem Lett (2011) 21: 3743-8 [PMID:21561767]
ABL proto-oncogene 1, non-receptor tyrosine kinase in Human [GtoPdb: 1923] [UniProtKB: P00519]
GtoPdb	-	-	9.7	pIC50	0.2	nM	IC50	Bioorg Med Chem Lett (2011) 21: 3743-8 [PMID:21561767]
ret proto-oncogene in Human [GtoPdb: 2185] [UniProtKB: P07949]
GtoPdb	-	-	9.7	pIC50	0.2	nM	IC50	Bioorg Med Chem Lett (2011) 21: 3743-8 [PMID:21561767]

ChEMBL data shown on this page come from version 36:

Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]