BMS-690514 [Ligand Id: 7879] activity data from GtoPdb

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  • epidermal growth factor receptor in Human [GtoPdb: 1797] [UniProtKB: P00533]
Created with Highcharts 10.3.3ValuesChart context menuepidermal growth factor receptorpKd HumanpKi HumanpIC50 HumanpEC50 Human0246810Highcharts.com
  • fms related receptor tyrosine kinase 3 in Human [GtoPdb: 1807] [UniProtKB: P36888]
Created with Highcharts 10.3.3ValuesChart context menufms related receptor tyrosine kinase 3pKd HumanpKi HumanpIC50 HumanpEC50 Human02468Highcharts.com
  • kinase insert domain receptor in Human [GtoPdb: 1813] [UniProtKB: P35968]
Created with Highcharts 10.3.3ValuesChart context menukinase insert domain receptorpKd HumanpKi HumanpIC50 HumanpEC50 Human02468Highcharts.com
  • erb-b2 receptor tyrosine kinase 2 in Human [GtoPdb: 2019] [UniProtKB: P04626]
Created with Highcharts 10.3.3ValuesChart context menuerb-b2 receptor tyrosine kinase 2pKd HumanpKi HumanpIC50 HumanpEC50 Human0246810Highcharts.com
DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
epidermal growth factor receptor in Human [GtoPdb: 1797] [UniProtKB: P00533]
GtoPdb - - 8.3 pIC50 5 nM IC50 J Pharm Sci (2010) 99: 3579-93 [PMID:20166197]
fms related receptor tyrosine kinase 3 in Human [GtoPdb: 1807] [UniProtKB: P36888]
GtoPdb - - 6.96 pIC50 110 nM IC50 J Pharm Sci (2010) 99: 3579-93 [PMID:20166197]
kinase insert domain receptor in Human [GtoPdb: 1813] [UniProtKB: P35968]
GtoPdb - - 7.3 pIC50 50 nM IC50 J Pharm Sci (2010) 99: 3579-93 [PMID:20166197]
erb-b2 receptor tyrosine kinase 2 in Human [GtoPdb: 2019] [UniProtKB: P04626]
GtoPdb - - 7.72 pIC50 19 nM IC50 J Pharm Sci (2010) 99: 3579-93 [PMID:20166197]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.