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ChEMBL ligand: CHEMBL42280 (L-adrenaline) |
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DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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β1-adrenoceptor/Beta-1 adrenergic receptor in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3252] [GtoPdb: 28] [UniProtKB: P18090] | ||||||||
ChEMBL | Binding of [3H]dihydroalprenolol to beta-1 adrenergic receptor of rat cerebral cortical membranes | B | 4.89 | pKi | 13000 | nM | Ki | J. Med. Chem. (2000) 43: 1611-1619 [PMID:10780918] |
Beta-2 adrenergic receptor in Dog (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2289] [UniProtKB: P54833] | ||||||||
ChEMBL | Binding of [3H]dihydroalprenolol to beta-2 adrenergic receptor of rat cerebral cortical membranes | B | 5.43 | pKi | 3700 | nM | Ki | J. Med. Chem. (2000) 43: 1611-1619 [PMID:10780918] |
α1A-adrenoceptor in Human [GtoPdb: 22] [UniProtKB: P35348] | ||||||||
GtoPdb | - | - | 5 | pKi | - | - | - | Mol Pharmacol (1995) 48: 250-8 [PMID:7651358] |
α1B-adrenoceptor in Human [GtoPdb: 23] [UniProtKB: P35368] | ||||||||
GtoPdb | - | - | 5.1 | pKi | - | - | - | Mol Pharmacol (1995) 48: 250-8 [PMID:7651358] |
α1D-adrenoceptor in Human [GtoPdb: 24] [UniProtKB: P25100] | ||||||||
GtoPdb | - | - | 6 | pKi | - | - | - | Mol Pharmacol (1995) 48: 250-8 [PMID:7651358] |
ChEMBL data shown on this page come from version 31:
Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]