GSK Compound 34 [Ligand Id: 3502] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL1082152
  • cyclin dependent kinase 19/Cell division cycle 2-like protein kinase 6 in Human [ChEMBL: CHEMBL6002] [GtoPdb: 1972] [UniProtKB: Q9BWU1]
Created with Highcharts 10.3.3ValuesChart context menuCell division cycle 2-like protein kinase 6pKd HumanpKi HumanpIC50 HumanpEC50 Human012345Highcharts.com
  • cyclin dependent kinase 8/Cell division protein kinase 8 in Human [ChEMBL: CHEMBL5719] [GtoPdb: 1980] [UniProtKB: P49336]
Created with Highcharts 10.3.3ValuesChart context menuCell division protein kinase 8pKd HumanpKi HumanpIC50 HumanpEC50 Human012345Highcharts.com
  • cyclin dependent kinase 2/Cyclin-dependent kinase 2 in Human [ChEMBL: CHEMBL301] [GtoPdb: 1973] [UniProtKB: P24941]
Created with Highcharts 10.3.3ValuesChart context menuCyclin-dependent kinase 2pKd HumanpKi HumanpIC50 HumanpEC50 Human02468Highcharts.com
  • cyclin dependent kinase 3/Cyclin-dependent kinase 3 in Human [ChEMBL: CHEMBL4442] [GtoPdb: 1975] [UniProtKB: Q00526]
Created with Highcharts 10.3.3ValuesChart context menuCyclin-dependent kinase 3pKd HumanpKi HumanpIC50 HumanpEC50 Human02468Highcharts.com
  • cyclin dependent kinase 5/Cyclin-dependent kinase 5 in Human [ChEMBL: CHEMBL4036] [GtoPdb: 1977] [UniProtKB: Q00535]
Created with Highcharts 10.3.3ValuesChart context menuCyclin-dependent kinase 5pKd HumanpKi HumanpIC50 HumanpEC50 Human0123456Highcharts.com
  • cyclin dependent kinase 7/Cyclin-dependent kinase 7 in Human [ChEMBL: CHEMBL3055] [GtoPdb: 1979] [UniProtKB: P50613]
Created with Highcharts 10.3.3ValuesChart context menuCyclin-dependent kinase 7pKd HumanpKi HumanpIC50 HumanpEC50 Human02468Highcharts.com
  • cyclin dependent kinase 9/Cyclin-dependent kinase 9 in Human [ChEMBL: CHEMBL3116] [GtoPdb: 1981] [UniProtKB: P50750]
Created with Highcharts 10.3.3ValuesChart context menuCyclin-dependent kinase 9pKd HumanpKi HumanpIC50 HumanpEC50 Human02468Highcharts.com
  • CDC like kinase 1/Dual specificity protein kinase CLK1 in Human [ChEMBL: CHEMBL4224] [GtoPdb: 1990] [UniProtKB: P49759]
Created with Highcharts 10.3.3ValuesChart context menuDual specificity protein kinase CLK1pKd HumanpKi HumanpIC50 HumanpEC50 Human0246810Highcharts.com
  • CDC like kinase 2/Dual specificity protein kinase CLK2 in Human [ChEMBL: CHEMBL4225] [GtoPdb: 1991] [UniProtKB: P49760]
Created with Highcharts 10.3.3ValuesChart context menuDual specificity protein kinase CLK2pKd HumanpKi HumanpIC50 HumanpEC50 Human0246810Highcharts.com
  • CDC like kinase 3/Dual specificity protein kinase CLK3 in Human [ChEMBL: CHEMBL4226] [GtoPdb: 1992] [UniProtKB: P49761]
Created with Highcharts 10.3.3ValuesChart context menuDual specificity protein kinase CLK3pKd HumanpKi HumanpIC50 HumanpEC50 Human02468Highcharts.com
  • CDC like kinase 4/Dual specificity protein kinase CLK4 in Human [ChEMBL: CHEMBL4203] [GtoPdb: 1993] [UniProtKB: Q9HAZ1]
Created with Highcharts 10.3.3ValuesChart context menuDual specificity protein kinase CLK4pKd HumanpKi HumanpIC50 HumanpEC50 Human02468Highcharts.com
  • TTK protein kinase/Dual specificity protein kinase TTK in Human [ChEMBL: CHEMBL3983] [GtoPdb: 2264] [UniProtKB: P33981]
Created with Highcharts 10.3.3ValuesChart context menuDual specificity protein kinase TTKpKd HumanpKi HumanpIC50 HumanpEC50 Human0123456Highcharts.com
  • dual specificity tyrosine phosphorylation regulated kinase 1B/Dual specificity tyrosine-phosphorylation-regulated kinase 1B in Human [ChEMBL: CHEMBL5543] [GtoPdb: 2010] [UniProtKB: Q9Y463]
Created with Highcharts 10.3.3ValuesChart context menuDual specificity tyrosine-phosphorylation-regulated kinase 1BpKd HumanpKi HumanpIC50 HumanpEC50 Human02468Highcharts.com
  • glycogen synthase kinase 3 alpha/Glycogen synthase kinase-3 alpha in Human [ChEMBL: CHEMBL2850] [GtoPdb: 2029] [UniProtKB: P49840]
Created with Highcharts 10.3.3ValuesChart context menuGlycogen synthase kinase-3 alphapKd HumanpKi HumanpIC50 HumanpEC50 Human0246810Highcharts.com
  • glycogen synthase kinase 3 beta/Glycogen synthase kinase-3 beta in Human [ChEMBL: CHEMBL262] [GtoPdb: 2030] [UniProtKB: P49841]
Created with Highcharts 10.3.3ValuesChart context menuGlycogen synthase kinase-3 betapKd HumanpKi HumanpIC50 HumanpEC50 Human024681012Highcharts.com
  • eukaryotic translation initiation factor 2 alpha kinase 2/Interferon-induced, double-stranded RNA-activated protein kinase in Human [ChEMBL: CHEMBL5785] [GtoPdb: 2016] [UniProtKB: P19525]
Created with Highcharts 10.3.3ValuesChart context menuInterferon-induced, double-stranded RNA-activated protein kinasepKd HumanpKi HumanpIC50 HumanpEC50 Human0123456Highcharts.com
  • mitogen-activated protein kinase 3/MAP kinase ERK1 in Human [ChEMBL: CHEMBL3385] [GtoPdb: 1494] [UniProtKB: P27361]
Created with Highcharts 10.3.3ValuesChart context menuMAP kinase ERK1pKd HumanpKi HumanpIC50 HumanpEC50 Human012345Highcharts.com
  • mitogen-activated protein kinase 1/MAP kinase ERK2 in Human [ChEMBL: CHEMBL4040] [GtoPdb: 1495] [UniProtKB: P28482]
Created with Highcharts 10.3.3ValuesChart context menuMAP kinase ERK2pKd HumanpKi HumanpIC50 HumanpEC50 Human012345Highcharts.com
  • mitogen-activated protein kinase 15/Mitogen-activated protein kinase 15 in Human [ChEMBL: CHEMBL5198] [GtoPdb: 2090] [UniProtKB: Q8TD08]
Created with Highcharts 10.3.3ValuesChart context menuMitogen-activated protein kinase 15pKd HumanpKi HumanpIC50 HumanpEC50 Human02468Highcharts.com
  • mitogen-activated protein kinase 4/Mitogen-activated protein kinase 4 in Human [ChEMBL: CHEMBL5759] [GtoPdb: 2091] [UniProtKB: P31152]
Created with Highcharts 10.3.3ValuesChart context menuMitogen-activated protein kinase 4pKd HumanpKi HumanpIC50 HumanpEC50 Human012345Highcharts.com
  • mitogen-activated protein kinase 6/Mitogen-activated protein kinase 6 in Human [ChEMBL: CHEMBL5121] [GtoPdb: 2092] [UniProtKB: Q16659]
Created with Highcharts 10.3.3ValuesChart context menuMitogen-activated protein kinase 6pKd HumanpKi HumanpIC50 HumanpEC50 Human012345Highcharts.com
  • mitogen-activated protein kinase 7/Mitogen-activated protein kinase 7 in Human [ChEMBL: CHEMBL5332] [GtoPdb: 2093] [UniProtKB: Q13164]
Created with Highcharts 10.3.3ValuesChart context menuMitogen-activated protein kinase 7pKd HumanpKi HumanpIC50 HumanpEC50 Human0123456Highcharts.com
  • protein kinase C alpha/Protein kinase C alpha in Human [ChEMBL: CHEMBL299] [GtoPdb: 1482] [UniProtKB: P17252]
Created with Highcharts 10.3.3ValuesChart context menuProtein kinase C alphapKd HumanpKi HumanpIC50 HumanpEC50 Human02468Highcharts.com
  • serine/threonine kinase 16/Serine/threonine-protein kinase 16 in Human [ChEMBL: CHEMBL3938] [GtoPdb: 2213] [UniProtKB: O75716]
Created with Highcharts 10.3.3ValuesChart context menuSerine/threonine-protein kinase 16pKd HumanpKi HumanpIC50 HumanpEC50 Human02468Highcharts.com
  • aurora kinase A/Serine/threonine-protein kinase Aurora-A in Human [ChEMBL: CHEMBL4722] [GtoPdb: 1936] [UniProtKB: O14965]
Created with Highcharts 10.3.3ValuesChart context menuSerine/threonine-protein kinase Aurora-ApKd HumanpKi HumanpIC50 HumanpEC50 Human012345Highcharts.com
  • aurora kinase B/Serine/threonine-protein kinase Aurora-B in Human [ChEMBL: CHEMBL2185] [GtoPdb: 1937] [UniProtKB: Q96GD4]
Created with Highcharts 10.3.3ValuesChart context menuSerine/threonine-protein kinase Aurora-BpKd HumanpKi HumanpIC50 HumanpEC50 Human012345Highcharts.com
  • aurora kinase C/Serine/threonine-protein kinase Aurora-C in Human [ChEMBL: CHEMBL3935] [GtoPdb: 1938] [UniProtKB: Q9UQB9]
Created with Highcharts 10.3.3ValuesChart context menuSerine/threonine-protein kinase Aurora-CpKd HumanpKi HumanpIC50 HumanpEC50 Human012345Highcharts.com
  • cyclin dependent kinase 16/Serine/threonine-protein kinase PCTAIRE-1 in Human [ChEMBL: CHEMBL4597] [GtoPdb: 1969] [UniProtKB: Q00536]
Created with Highcharts 10.3.3ValuesChart context menuSerine/threonine-protein kinase PCTAIRE-1pKd HumanpKi HumanpIC50 HumanpEC50 Human0246810Highcharts.com
  • cyclin dependent kinase 17/Serine/threonine-protein kinase PCTAIRE-2 in Human [ChEMBL: CHEMBL5790] [GtoPdb: 1970] [UniProtKB: Q00537]
Created with Highcharts 10.3.3ValuesChart context menuSerine/threonine-protein kinase PCTAIRE-2pKd HumanpKi HumanpIC50 HumanpEC50 Human02468Highcharts.com
  • cyclin dependent kinase 18/Serine/threonine-protein kinase PCTAIRE-3 in Human [ChEMBL: CHEMBL5316] [GtoPdb: 1971] [UniProtKB: Q07002]
Created with Highcharts 10.3.3ValuesChart context menuSerine/threonine-protein kinase PCTAIRE-3pKd HumanpKi HumanpIC50 HumanpEC50 Human02468Highcharts.com
  • polo like kinase 1/Serine/threonine-protein kinase PLK1 in Human [ChEMBL: CHEMBL3024] [GtoPdb: 2168] [UniProtKB: P53350]
Created with Highcharts 10.3.3ValuesChart context menuSerine/threonine-protein kinase PLK1pKd HumanpKi HumanpIC50 HumanpEC50 Human012345Highcharts.com
  • polo like kinase 3/Serine/threonine-protein kinase PLK3 in Human [ChEMBL: CHEMBL4897] [GtoPdb: 2170] [UniProtKB: Q9H4B4]
Created with Highcharts 10.3.3ValuesChart context menuSerine/threonine-protein kinase PLK3pKd HumanpKi HumanpIC50 HumanpEC50 Human012345Highcharts.com
  • polo like kinase 4/Serine/threonine-protein kinase PLK4 in Human [ChEMBL: CHEMBL3788] [GtoPdb: 2171] [UniProtKB: O00444]
Created with Highcharts 10.3.3ValuesChart context menuSerine/threonine-protein kinase PLK4pKd HumanpKi HumanpIC50 HumanpEC50 Human02468Highcharts.com
  • CCR2 in Human [GtoPdb: 59] [UniProtKB: P41597]
Created with Highcharts 10.3.3ValuesChart context menuCCR2pKd HumanpKi HumanpIC50 HumanpEC50 Human02468Highcharts.com
DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
cyclin dependent kinase 19/Cell division cycle 2-like protein kinase 6 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL6002] [GtoPdb: 1972] [UniProtKB: Q9BWU1]
ChEMBL Inhibition of CDK11 B 4.4 pKd 40000 nM Kd Bioorg Med Chem Lett (2010) 20: 1693-1696 [PMID:20138512]
cyclin dependent kinase 8/Cell division protein kinase 8 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5719] [GtoPdb: 1980] [UniProtKB: P49336]
ChEMBL Inhibition of CDK8 B 4.4 pKd 40000 nM Kd Bioorg Med Chem Lett (2010) 20: 1693-1696 [PMID:20138512]
cyclin dependent kinase 2/Cyclin-dependent kinase 2 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL301] [GtoPdb: 1973] [UniProtKB: P24941]
ChEMBL Inhibition of CDK2 B 6.82 pKd 150 nM Kd Bioorg Med Chem Lett (2010) 20: 1693-1696 [PMID:20138512]
cyclin dependent kinase 3/Cyclin-dependent kinase 3 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4442] [GtoPdb: 1975] [UniProtKB: Q00526]
ChEMBL Inhibition of CDK3 B 7.1 pKd 80 nM Kd Bioorg Med Chem Lett (2010) 20: 1693-1696 [PMID:20138512]
cyclin dependent kinase 5/Cyclin-dependent kinase 5 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4036] [GtoPdb: 1977] [UniProtKB: Q00535]
ChEMBL Inhibition of CDK5 B 5.17 pKd 6800 nM Kd Bioorg Med Chem Lett (2010) 20: 1693-1696 [PMID:20138512]
cyclin dependent kinase 7/Cyclin-dependent kinase 7 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3055] [GtoPdb: 1979] [UniProtKB: P50613]
ChEMBL Inhibition of CDK7 B 7.39 pKd 41 nM Kd Bioorg Med Chem Lett (2010) 20: 1693-1696 [PMID:20138512]
cyclin dependent kinase 9/Cyclin-dependent kinase 9 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3116] [GtoPdb: 1981] [UniProtKB: P50750]
ChEMBL Inhibition of CDK9 B 6.39 pKd 410 nM Kd Bioorg Med Chem Lett (2010) 20: 1693-1696 [PMID:20138512]
CDC like kinase 1/Dual specificity protein kinase CLK1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4224] [GtoPdb: 1990] [UniProtKB: P49759]
ChEMBL Inhibition of CLK1 B 7.8 pKd 16 nM Kd Bioorg Med Chem Lett (2010) 20: 1693-1696 [PMID:20138512]
CDC like kinase 2/Dual specificity protein kinase CLK2 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4225] [GtoPdb: 1991] [UniProtKB: P49760]
ChEMBL Inhibition of CLK2 B 8 pKd 10 nM Kd Bioorg Med Chem Lett (2010) 20: 1693-1696 [PMID:20138512]
CDC like kinase 3/Dual specificity protein kinase CLK3 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4226] [GtoPdb: 1992] [UniProtKB: P49761]
ChEMBL Inhibition of CLK3 B 6.51 pKd 310 nM Kd Bioorg Med Chem Lett (2010) 20: 1693-1696 [PMID:20138512]
CDC like kinase 4/Dual specificity protein kinase CLK4 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4203] [GtoPdb: 1993] [UniProtKB: Q9HAZ1]
ChEMBL Inhibition of CLK4 B 6.96 pKd 110 nM Kd Bioorg Med Chem Lett (2010) 20: 1693-1696 [PMID:20138512]
TTK protein kinase/Dual specificity protein kinase TTK in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3983] [GtoPdb: 2264] [UniProtKB: P33981]
ChEMBL Inhibition of TTK B 5.17 pKd 6700 nM Kd Bioorg Med Chem Lett (2010) 20: 1693-1696 [PMID:20138512]
dual specificity tyrosine phosphorylation regulated kinase 1B/Dual specificity tyrosine-phosphorylation-regulated kinase 1B in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5543] [GtoPdb: 2010] [UniProtKB: Q9Y463]
ChEMBL Inhibition of DYRK1B B 7.06 pKd 87 nM Kd Bioorg Med Chem Lett (2010) 20: 1693-1696 [PMID:20138512]
glycogen synthase kinase 3 alpha/Glycogen synthase kinase-3 alpha in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2850] [GtoPdb: 2029] [UniProtKB: P49840]
ChEMBL Inhibition of GSK3alpha B 8.82 pKd 1.5 nM Kd Bioorg Med Chem Lett (2010) 20: 1693-1696 [PMID:20138512]
glycogen synthase kinase 3 beta/Glycogen synthase kinase-3 beta in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL262] [GtoPdb: 2030] [UniProtKB: P49841]
ChEMBL Inhibition of human recombinant GSK3-beta assessed as [gamma33]ATP transfer to biotinylated CREB-peptide substrate after 1 hr by scintillation counting B 10.28 pKd 0.05 nM Kd Bioorg Med Chem Lett (2010) 20: 1693-1696 [PMID:20138512]
ChEMBL Inhibition of human recombinant GSK3-beta assessed as [gamma33]ATP transfer to biotinylated CREB-peptide substrate after 1 hr by scintillation counting B 9.22 pIC50 0.6 nM IC50 Bioorg Med Chem Lett (2010) 20: 1693-1696 [PMID:20138512]
eukaryotic translation initiation factor 2 alpha kinase 2/Interferon-induced, double-stranded RNA-activated protein kinase in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5785] [GtoPdb: 2016] [UniProtKB: P19525]
ChEMBL Inhibition of PRKR B 4.85 pKd 14000 nM Kd Bioorg Med Chem Lett (2010) 20: 1693-1696 [PMID:20138512]
mitogen-activated protein kinase 3/MAP kinase ERK1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3385] [GtoPdb: 1494] [UniProtKB: P27361]
ChEMBL Inhibition of ERK1 B 4.4 pKd 40000 nM Kd Bioorg Med Chem Lett (2010) 20: 1693-1696 [PMID:20138512]
mitogen-activated protein kinase 1/MAP kinase ERK2 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4040] [GtoPdb: 1495] [UniProtKB: P28482]
ChEMBL Inhibition of ERK2 B 4.4 pKd 40000 nM Kd Bioorg Med Chem Lett (2010) 20: 1693-1696 [PMID:20138512]
mitogen-activated protein kinase 15/Mitogen-activated protein kinase 15 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5198] [GtoPdb: 2090] [UniProtKB: Q8TD08]
ChEMBL Inhibition of ERK8 B 7.49 pKd 32 nM Kd Bioorg Med Chem Lett (2010) 20: 1693-1696 [PMID:20138512]
mitogen-activated protein kinase 4/Mitogen-activated protein kinase 4 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5759] [GtoPdb: 2091] [UniProtKB: P31152]
ChEMBL Inhibition of ERK4 B 4.4 pKd 40000 nM Kd Bioorg Med Chem Lett (2010) 20: 1693-1696 [PMID:20138512]
mitogen-activated protein kinase 6/Mitogen-activated protein kinase 6 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5121] [GtoPdb: 2092] [UniProtKB: Q16659]
ChEMBL Inhibition of ERK3 B 4.4 pKd 40000 nM Kd Bioorg Med Chem Lett (2010) 20: 1693-1696 [PMID:20138512]
mitogen-activated protein kinase 7/Mitogen-activated protein kinase 7 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5332] [GtoPdb: 2093] [UniProtKB: Q13164]
ChEMBL Inhibition of ERK5 B 5.25 pKd 5600 nM Kd Bioorg Med Chem Lett (2010) 20: 1693-1696 [PMID:20138512]
protein kinase C alpha/Protein kinase C alpha in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL299] [GtoPdb: 1482] [UniProtKB: P17252]
ChEMBL Inhibition of PKCalpha B 6.4 pIC50 400 nM IC50 Bioorg Med Chem Lett (2010) 20: 1693-1696 [PMID:20138512]
serine/threonine kinase 16/Serine/threonine-protein kinase 16 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3938] [GtoPdb: 2213] [UniProtKB: O75716]
ChEMBL Inhibition of STK16 B 6.64 pKd 230 nM Kd Bioorg Med Chem Lett (2010) 20: 1693-1696 [PMID:20138512]
aurora kinase A/Serine/threonine-protein kinase Aurora-A in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4722] [GtoPdb: 1936] [UniProtKB: O14965]
ChEMBL Inhibition of AURKA B 4.4 pKd 40000 nM Kd Bioorg Med Chem Lett (2010) 20: 1693-1696 [PMID:20138512]
aurora kinase B/Serine/threonine-protein kinase Aurora-B in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2185] [GtoPdb: 1937] [UniProtKB: Q96GD4]
ChEMBL Inhibition of AURKB B 4.4 pKd 40000 nM Kd Bioorg Med Chem Lett (2010) 20: 1693-1696 [PMID:20138512]
aurora kinase C/Serine/threonine-protein kinase Aurora-C in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3935] [GtoPdb: 1938] [UniProtKB: Q9UQB9]
ChEMBL Inhibition of AURKC B 4.64 pKd 23000 nM Kd Bioorg Med Chem Lett (2010) 20: 1693-1696 [PMID:20138512]
cyclin dependent kinase 16/Serine/threonine-protein kinase PCTAIRE-1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4597] [GtoPdb: 1969] [UniProtKB: Q00536]
ChEMBL Inhibition of PCTK1 B 7.92 pKd 12 nM Kd Bioorg Med Chem Lett (2010) 20: 1693-1696 [PMID:20138512]
cyclin dependent kinase 17/Serine/threonine-protein kinase PCTAIRE-2 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5790] [GtoPdb: 1970] [UniProtKB: Q00537]
ChEMBL Inhibition of PCTK2 B 7.16 pKd 69 nM Kd Bioorg Med Chem Lett (2010) 20: 1693-1696 [PMID:20138512]
cyclin dependent kinase 18/Serine/threonine-protein kinase PCTAIRE-3 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5316] [GtoPdb: 1971] [UniProtKB: Q07002]
ChEMBL Inhibition of PCTK3 B 6.96 pKd 110 nM Kd Bioorg Med Chem Lett (2010) 20: 1693-1696 [PMID:20138512]
polo like kinase 1/Serine/threonine-protein kinase PLK1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3024] [GtoPdb: 2168] [UniProtKB: P53350]
ChEMBL Inhibition of PLK1 B 4.64 pKd 23000 nM Kd Bioorg Med Chem Lett (2010) 20: 1693-1696 [PMID:20138512]
polo like kinase 3/Serine/threonine-protein kinase PLK3 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4897] [GtoPdb: 2170] [UniProtKB: Q9H4B4]
ChEMBL Inhibition of PLK3 B 4.4 pKd 40000 nM Kd Bioorg Med Chem Lett (2010) 20: 1693-1696 [PMID:20138512]
polo like kinase 4/Serine/threonine-protein kinase PLK4 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3788] [GtoPdb: 2171] [UniProtKB: O00444]
ChEMBL Inhibition of PLK4 B 6.49 pKd 320 nM Kd Bioorg Med Chem Lett (2010) 20: 1693-1696 [PMID:20138512]
CCR2 in Human [GtoPdb: 59] [UniProtKB: P41597]
GtoPdb - - 7.6 pKi 25.1 nM Ki

ChEMBL data shown on this page come from version 35:

Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]