cicaprost [Ligand Id: 1917] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL160629 (Cicaprost)
  • EP1 receptor in Human [GtoPdb: 340] [UniProtKB: P34995]
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  • EP2 receptor in Mouse [GtoPdb: 341] [UniProtKB: Q62053]
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  • EP3 receptor in Human [GtoPdb: 342] [UniProtKB: P43115]
  • EP3 receptor in Mouse [GtoPdb: 342] [UniProtKB: P30557]
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  • EP4 receptor in Human [GtoPdb: 343] [UniProtKB: P35408]
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  • IP receptor in Human [GtoPdb: 345] [UniProtKB: P43119]
  • IP receptor in Mouse [GtoPdb: 345] [UniProtKB: P43252]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
EP1 receptor in Human [GtoPdb: 340] [UniProtKB: P34995]
GtoPdb - - 5.9 pKi - - - Biochim Biophys Acta (2000) 1483: 285-93 [PMID:10634944]
EP2 receptor in Mouse [GtoPdb: 341] [UniProtKB: Q62053]
GtoPdb - - 5.9 pKi - - - Br J Pharmacol (1997) 122: 217-24 [PMID:9313928]
EP3 receptor in Human [GtoPdb: 342] [UniProtKB: P43115]
GtoPdb - - 6.59 pKi 255 nM Ki Biochim Biophys Acta (2000) 1483: 285-93 [PMID:10634944]
EP3 receptor in Mouse [GtoPdb: 342] [UniProtKB: P30557]
GtoPdb - - 6.77 pKi 170 nM Ki Br J Pharmacol (1997) 122: 217-24 [PMID:9313928]
EP4 receptor in Human [GtoPdb: 343] [UniProtKB: P35408]
GtoPdb - - 7.4 pKi - - - Biochim Biophys Acta (2000) 1483: 285-93 [PMID:10634944]
IP receptor in Human [GtoPdb: 345] [UniProtKB: P43119]
GtoPdb - - 7.8 pKi - - - Biochim Biophys Acta (2000) 1483: 285-93 [PMID:10634944]
IP receptor in Mouse [GtoPdb: 345] [UniProtKB: P43252]
GtoPdb - - 8 pKi - - - Br J Pharmacol (1997) 122: 217-24 [PMID:9313928]

ChEMBL data shown on this page come from version 28:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]