UAWJ9-36-3 [Ligand Id: 11701] activity data from GtoPdb

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  • calpain 1 in Human [GtoPdb: 2336] [UniProtKB: P07384]
Created with Highcharts 10.3.3ValuesChart context menucalpain 1pKd HumanpKi HumanpIC50 HumanpEC50 Human012345Highcharts.com
  • cathepsin K in Human [GtoPdb: 2350] [UniProtKB: P43235]
Created with Highcharts 10.3.3ValuesChart context menucathepsin KpKd HumanpKi HumanpIC50 HumanpEC50 Human02468Highcharts.com
  • cathepsin L in Human [GtoPdb: 2351] [UniProtKB: P07711]
Created with Highcharts 10.3.3ValuesChart context menucathepsin LpKd HumanpKi HumanpIC50 HumanpEC50 Human01234567Highcharts.com
  • CoV 3C-like (main) protease in SARS-CoV [GtoPdb: 3111] [UniProtKB: P0C6U8]
Created with Highcharts 10.3.3ValuesChart context menuCoV 3C-like (main) proteasepKd SARS-CoVpKi SARS-CoVpIC50 SARS-CoVpEC50 SARS-CoV02468Highcharts.com
DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
calpain 1 in Human [GtoPdb: 2336] [UniProtKB: P07384]
GtoPdb inactive - 4.7 pIC50 >20000 nM IC50 ACS Pharmacol Transl Sci (2021) 4: 1408-1421 [PMID:34414360]
cathepsin K in Human [GtoPdb: 2350] [UniProtKB: P43235]
GtoPdb - - 7.38 pIC50 42 nM IC50 ACS Pharmacol Transl Sci (2021) 4: 1408-1421 [PMID:34414360]
cathepsin L in Human [GtoPdb: 2351] [UniProtKB: P07711]
GtoPdb - - 5.74 pIC50 1810 nM IC50 ACS Pharmacol Transl Sci (2021) 4: 1408-1421 [PMID:34414360]
CoV 3C-like (main) protease in SARS-CoV [GtoPdb: 3111] [UniProtKB: P0C6U8]
GtoPdb - - 7 pIC50 99 nM IC50 ACS Pharmacol Transl Sci (2021) 4: 1408-1421 [PMID:34414360]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.