ML300 [Ligand Id: 11657] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL2442081 |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| CYP1A2/Cytochrome P450 1A2 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3356] [GtoPdb: 1319] [UniProtKB: P05177] | ||||||||
| ChEMBL | Inhibition of CYP1A2 (unknown origin) | B | 5.11 | pIC50 | 7700 | nM | IC50 | J Med Chem (2022) 65: 2880-2904 [PMID:34347470] |
| CoV 3C-like (main) protease in SARS-CoV [GtoPdb: 3111] [UniProtKB: P0C6U8] | ||||||||
| GtoPdb | - | - | 5.35 | pIC50 | 4450 | nM | IC50 | J Med Chem (2022) 65: 2880-2904 [PMID:34347470] |
| GtoPdb | - | - | 5.39 | pIC50 | 4100 | nM | IC50 | Bioorg Med Chem Lett (2013) 23: 6172-7 [PMID:24080461] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
