TTT-3002 [Ligand Id: 11134] activity data from GtoPdb
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| fms related receptor tyrosine kinase 3 in Human [GtoPdb: 1807] [UniProtKB: P36888] | ||||||||
| GtoPdb | Inhibition of FLT3 phosphorylation in Molm14 human leukemia cells that carry the FLT3/ITD activation mutation | - | 9.14 | pIC50 | 0.72 | nM | IC50 | Blood (2014) 123: 1525-34 [PMID:24408321] |
| leucine rich repeat kinase 2 in Human [GtoPdb: 2059] [UniProtKB: Q5S007] | ||||||||
| GtoPdb | Measuring inhibition of LRRK2-catalyzed phosphorylation of the specific peptide substrate LRRKtide iv vitro | - | 9.15 | pIC50 | 0.7 | nM | IC50 | Hum Mol Genet (2013) 22: 328-44 [PMID:23065705] |
Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.
