Plasmodium asexual blood stage (erythrocytic merozoite, trophozoite, erythrocytic schizont)
Help on GtoMPdb Parasite Lifecycle Data
The GtoMPdb contains data detailing the parasitic lifecycle activity for antimalarial ligands and their target interactions. Top-level Plasmodium lifecycle stages (collective categories for one or more developmental forms of the parasite) have been defined by GtoMPdb against which interactions in the database have been annotated.
Each individual Parasite Lifecycle Stage page provides a detailed description of the stage and a table displaying all interactions (contained in the database) associated with it.
✖| Stage ID: | 3 | |
| Name: | Plasmodium asexual blood stage (erythrocytic merozoite, trophozoite, erythrocytic schizont) | |
| Associated with: | 33 targets | |
| 118 ligands | ||
| Description |
The collective lifecycle stage that occurs as a result of asexual replication in erythrocytes of the host organism and can include:
It is the repeated cycles of schizogony in erythrocytes that leads to clinical symptoms: the simultaneous rupture of infected erythrocytes and the associated release of antigens and waste products accounts for the intermittent bouts of fever associated with malaria. As a result, almost all available antimalarial therapies target the asexual blood stage. |
Interactions
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