Top ▲

Interferon-λ receptor subunit 1

Click here for help

Immunopharmacology Ligand  Target has curated data in GtoImmuPdb

Target id: 1733

Nomenclature: Interferon-λ receptor subunit 1

Family: IL-10 receptor family

Quaternary Structure: Complexes
Interferon-λ receptor 1
Gene and Protein Information Click here for help
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human 1 520 1p36.11 IFNLR1 interferon lambda receptor 1
Mouse 1 535 4 D3 Ifnlr1 interferon lambda receptor 1
Rat - - Ifnlr1 interferon, lambda receptor 1
Previous and Unofficial Names Click here for help
CRF2/12 | IL-28R1 | interleukin 28 receptor alpha | interferon, lambda receptor 1 | interferon
Database Links Click here for help
ChEMBL Target
Ensembl Gene
Entrez Gene
Human Protein Atlas
Immunopharmacology Comments
Interferon-λ receptor subunit 1 is the ligand binding component of the functional heterodimeric receptor for interferons λ1, λ2 and λ3
Immuno Process Associations
Immuno Process:  Inflammation
GO Annotations:  Associated to 1 GO processes
GO:0034342 response to type III interferon ISS
Immuno Process:  Immune regulation
GO Annotations:  Associated to 1 GO processes
GO:0050691 regulation of defense response to virus by host IDA
Immuno Process:  Cytokine production & signalling
GO Annotations:  Associated to 3 GO processes
GO:0004896 cytokine receptor activity IBA
GO:0019221 cytokine-mediated signaling pathway IBA
GO:0034342 response to type III interferon ISS

How to cite this page

IL-10 receptor family: Interferon-λ receptor subunit 1. Last modified on 06/04/2017. Accessed on 01/12/2021. IUPHAR/BPS Guide to PHARMACOLOGY,