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IL-10 receptor family C

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

Overview

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The IL-10 family of receptors are heterodimeric combinations of family members: IL10RA/IL10RB responds to IL-10; IL20RA/IL20RB responds to IL-19, IL-20 and IL-24; IL22RA1/IL20RB responds to IL-20 and IL-24; IL22RA1/IL10RB responds to IL-22; IFNLR1(previouly known as IL28RA)/IL10RB responds to IFN-λ1, -λ2 and -λ3 (previouly known as IL-29, IL-28A and IL-28B respectively).

Receptors

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Targets of relevance to immunopharmacology are highlighted in blue

Complexes

Interleukin-10 receptor C Show summary » More detailed page go icon to follow link

Interleukin-20 receptor C Show summary » More detailed page go icon to follow link

Interleukin-22α1/20β heteromer C Show summary » More detailed page go icon to follow link

Interleukin-22α1/10β heteromer C Show summary » More detailed page go icon to follow link

Interferon-λ receptor 1 C Show summary » More detailed page go icon to follow link

Receptors and Subunits

Interleukin-22 receptor α2 C Show summary » More detailed page go icon to follow link

Interleukin 10 receptor, α subunit C Show summary » More detailed page go icon to follow link

Interleukin 10 receptor, β subunit C Show summary » More detailed page go icon to follow link

Interleukin 20 receptor, α subunit C Show summary » More detailed page go icon to follow link

Interleukin 20 receptor, β subunit C Show summary » More detailed page go icon to follow link

Interleukin 22 receptor, α1 subunit C Show summary » More detailed page go icon to follow link

Interferon-λ receptor subunit 1 C Show summary » More detailed page go icon to follow link

Further reading

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References

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How to cite this family page

Database page citation:

IL-10 receptor family. Accessed on 04/12/2024. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=311.

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Fabbro D, Kelly E, Mathie AA, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Davies JA et al. (2023) The Concise Guide to PHARMACOLOGY 2023/24: Catalytic receptors. Br J Pharmacol. 180 Suppl 2:S241-288.