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Target not currently curated in GtoImmuPdb
Target id: 1478
Nomenclature: protein kinase, cAMP-dependent, catalytic, gamma subunit
Abbreviated Name: PKACg
Family: Protein kinase A (PKA) family
Quaternary Structure: Complexes |
protein kinase A |
Gene and Protein Information | ||||||
Species | TM | AA | Chromosomal Location | Gene Symbol | Gene Name | Reference |
Human | - | 351 | 9q21.11 | PRKACG | protein kinase cAMP-activated catalytic subunit gamma |
Previous and Unofficial Names |
protein kinase, cAMP-dependent, gamma catalytic subunit |
Database Links | |
Alphafold | P22612 (Hs) |
BRENDA | 2.7.11.11 |
ChEMBL Target | CHEMBL2743 (Hs) |
Ensembl Gene | ENSG00000165059 (Hs) |
Entrez Gene | 5568 (Hs) |
Human Protein Atlas | ENSG00000165059 (Hs) |
KEGG Enzyme | 2.7.11.11 |
KEGG Gene | hsa:5568 (Hs) |
OMIM | 176893 (Hs) |
Pharos | P22612 (Hs) |
RefSeq Nucleotide | NM_002732 (Hs) |
RefSeq Protein | NP_002723 (Hs) |
UniProtKB | P22612 (Hs) |
Wikipedia | PRKACG (Hs) |
Enzyme Reaction | ||||
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EMD Millipore KinaseProfilerTM screen/Reaction Biology Kinase HotspotSM screen | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
A screen profiling 158 kinase inhibitors (Calbiochem Protein Kinase Inhibitor Library I and II, catalogue numbers 539744 and 539745) for their inhibitory activity at 1µM and 10µM against 234 human recombinant kinases using the EMD Millipore KinaseProfilerTM service. A screen profiling the inhibitory activity of 178 commercially available kinase inhibitors at 0.5µM against a panel of 300 recombinant protein kinases using the Reaction Biology Corporation Kinase HotspotSM platform. http://www.millipore.com/techpublications/tech1/pf3036 http://www.reactionbiology.com/webapps/main/pages/kinase.aspx Reference: ...1 |
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Target used in screen: nd/PKAcg | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Immuno Process Associations | ||
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Protein kinase A (PKA) family: protein kinase, cAMP-dependent, catalytic, gamma subunit. Last modified on 20/03/2013. Accessed on 02/12/2024. IUPHAR/BPS Guide to PHARMACOLOGY, https://www.guidetoimmunopharmacology.org/GRAC/ObjectDisplayForward?objectId=1478.