Synonyms: CI-366 | CN-10395 | PM-671 | Zarontin®
ethosuximide is an approved drug (FDA (1960))
Compound class:
Synthetic organic
Comment: Ethosuximide is a succinimide anticonvulsant. It is often preferred over valproic acid as it does not produce the same hepatotoxicity.
![]() View more information in the IUPHAR Pharmacology Education Project: ethosuximide |
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Classification ![]() |
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Compound class | Synthetic organic |
Approved drug? | Yes (FDA (1960)) |
Approved drug? | Yes. FDA (1960) |
WHO Essential Medicine | WHO Essential Medicines List (EML) (23rd List, 2023). Access PDF version. Click to view more information about the WHO Model Lists of Essential Medicines. |
IUPAC Name ![]() |
3-ethyl-5-hydroxy-3-methyl-3,4-dihydro-2H-pyrrol-2-one |
International Nonproprietary Names ![]() |
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INN number | INN |
1077 | ethosuximide |
Synonyms ![]() |
CI-366 | CN-10395 | PM-671 | Zarontin® |
Database Links ![]() |
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CAS Registry No. | 77-67-8 |
ChEMBL Ligand | CHEMBL696 |
DrugBank Ligand | DB00593 |
DrugCentral Ligand | 1087 |
GtoPdb PubChem SID | 178103757 |
PubChem CID | 3291 |
Search Google for chemical match using the InChIKey | HAPOVYFOVVWLRS-UHFFFAOYSA-N |
Search Google for chemicals with the same backbone | HAPOVYFOVVWLRS |
Search PubMed clinical trials | ethosuximide |
Search PubMed titles | ethosuximide |
Search PubMed titles/abstracts | ethosuximide |
UniChem Compound Search for chemical match using the InChIKey | HAPOVYFOVVWLRS-UHFFFAOYSA-N |
UniChem Connectivity Search for chemical match using the InChIKey | HAPOVYFOVVWLRS-UHFFFAOYSA-N |
Wikipedia | Ethosuximide |
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Ethosuximide (links to external site)
Cat. No. HY-B1378 |