diphenylpyraline   Click here for help

GtoPdb Ligand ID: 7165

Synonyms: Hispril®
Approved drug Immunopharmacology Ligand
diphenylpyraline is an approved drug
Compound class: Synthetic organic
Comment: Diphenylpyraline is a first-generation diphenylpiperidine antihistamine with anticholinergic effects.
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2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 4
Topological polar surface area 12.47
Molecular weight 281.18
XLogP 3.7
No. Lipinski's rules broken 0
SMILES / InChI / InChIKey
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Canonical SMILES CN1CCC(CC1)OC(c1ccccc1)c1ccccc1
Isomeric SMILES CN1CCC(CC1)OC(c1ccccc1)c1ccccc1
InChI InChI=1S/C19H23NO/c1-20-14-12-18(13-15-20)21-19(16-8-4-2-5-9-16)17-10-6-3-7-11-17/h2-11,18-19H,12-15H2,1H3
InChI Key OWQUZNMMYNAXSL-UHFFFAOYSA-N
Classification Click here for help
Compound class Synthetic organic
Approved drug? Yes
IUPAC Name Click here for help
4-(diphenylmethoxy)-1-methylpiperidine
International Nonproprietary Names Click here for help
INN number INN
695 diphenylpyraline
Synonyms Click here for help
Hispril®
Database Links Click here for help
CAS Registry No. 147-20-6
ChEMBL Ligand CHEMBL1492
DrugBank Ligand DB01146
DrugCentral Ligand 920
GtoPdb PubChem SID 178103740
PubChem CID 3103
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UniChem Compound Search for chemical match using the InChIKey OWQUZNMMYNAXSL-UHFFFAOYSA-N
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Wikipedia Diphenylpyraline