Synonyms: BMS986299 | compound 112 [WO2018152396A1]
Compound class:
Synthetic organic
Comment: BMS-986299 is a NLRP3 inflammasome modulator (agonist) [1]. It induces production of IL-1β and IL-8 and it is being examined for immunomodulatory and antineoplastic activities. Enhanced IL-8 is predicted to induce tumouricidal activity of natural killer (NK) cells against cancer cells.
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Classification | |
Compound class | Synthetic organic |
Synonyms |
BMS986299 | compound 112 [WO2018152396A1] |
Database Links | |
GtoPdb PubChem SID | 441604881 |
PubChem CID | 137498152 |
Search Google for chemical match using the InChIKey | UHNRLQRZRNKOKU-UHFFFAOYSA-N |
Search Google for chemicals with the same backbone | UHNRLQRZRNKOKU |
UniChem Compound Search for chemical match using the InChIKey | UHNRLQRZRNKOKU-UHFFFAOYSA-N |
UniChem Connectivity Search for chemical match using the InChIKey | UHNRLQRZRNKOKU-UHFFFAOYSA-N |