Synonyms: Mulpleta® | S-888711 | S888711
lusutrombopag is an approved drug (Japan (2015), FDA (2018), EMA (2019))
Compound class:
Synthetic organic
Comment: Lusutrombopag is an orally bioavailable, nonpeptidyl, small molecule thrombopoietin (TPO) receptor agonist [3] that was developed by Shionogi in Japan. It was the second TPO receptor agonist to receive FDA approval in 2018 (avatrombopag was the first).
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Classification | |
Compound class | Synthetic organic |
Approved drug? | Yes (Japan (2015), FDA (2018), EMA (2019)) |
IUPAC Name |
(E)-3-[2,6-dichloro-4-[[4-[3-[(1S)-1-hexoxyethyl]-2-methoxyphenyl]-1,3-thiazol-2-yl]carbamoyl]phenyl]-2-methylprop-2-enoic acid |
International Nonproprietary Names | |
INN number | INN |
9410 | lusutrombopag |
Synonyms |
Mulpleta® | S-888711 | S888711 |
Database Links | |
CAS Registry No. | 1110766-97-6 (source: PubChem) |
ChEMBL Ligand | CHEMBL2107831 |
DrugBank Ligand | DB13125 |
DrugCentral Ligand | 5059 |
GtoPdb PubChem SID | 375973220 |
PubChem CID | 49843517 |
Search Google for chemical match using the InChIKey | NOZIJMHMKORZBA-KJCUYJGMSA-N |
Search Google for chemicals with the same backbone | NOZIJMHMKORZBA |
Search PubMed clinical trials | lusutrombopag |
Search PubMed titles | lusutrombopag |
Search PubMed titles/abstracts | lusutrombopag |
UniChem Compound Search for chemical match using the InChIKey | NOZIJMHMKORZBA-KJCUYJGMSA-N |
UniChem Connectivity Search for chemical match using the InChIKey | NOZIJMHMKORZBA-KJCUYJGMSA-N |