OSI-930   Click here for help

GtoPdb Ligand ID: 9383

Synonyms: OSI 930 | OSI930
Compound class: Synthetic organic
Comment: OSI-930 is a multi-targeted kinase inhibitor, with potent inhibitory activity vs. Kit, KDR, CSF-1R, Flt1, c-Raf and Lck [1].
Click here for help
2D Structure
Click here for help
Click here for structure editor
Physico-chemical Properties
Click here for help
Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 8
Topological polar surface area 91.49
Molecular weight 443.09
XLogP 5.43
No. Lipinski's rules broken 1
Click here for help
Canonical SMILES O=C(c1sccc1NCc1ccnc2c1cccc2)Nc1ccc(cc1)OC(F)(F)F
Isomeric SMILES O=C(c1sccc1NCc1ccnc2c1cccc2)Nc1ccc(cc1)OC(F)(F)F
InChI InChI=1S/C22H16F3N3O2S/c23-22(24,25)30-16-7-5-15(6-8-16)28-21(29)20-19(10-12-31-20)27-13-14-9-11-26-18-4-2-1-3-17(14)18/h1-12,27H,13H2,(H,28,29)
Download 2D Structure Click here for help
Canonical SMILES Download
Isomeric SMILES Download
InChI standard identifier Download
InChI standard key Download

Molecular structure representations generated using Open Babel