Synonyms: compound 32 [PMID: 26861551]
Compound class:
Synthetic organic
Comment: GSK2245035 is reported as a selective Toll-like receptor 7 (TLR7) agonist, with potential clinical action as an intranasally administered anti-asthmatic [2]. It is Example 22 claimed in patent WO2010018133 [3].
The TLR7- IFNα pathway is a novel pathway being investigated for pharmacological intervention in allergic asthma. |
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Molecular structure representations generated using Open Babel