Synonyms: IL-12 p40 | IL-12B monomer | interleukin-12β | interleukin-12B | natural killer cell stimulatory factor 2
Compound class:
Endogenous peptide in human, mouse or rat
Comment: This is a subunit of bioactive IL-12.
Species: Human
|
Is a component of |
IL-12 |
IL-23 |
Post-translational Modification | |
N-linked glycosylation of asparagine residue at position 100; C-linked glycosylation of tryptophan at position 297, and disulphide bond formation between cysteine residues at positions 28 and 68, 109 and 120, 148 and 171, and 278 and 305. Predicted N-linked glycosylation of aspragibe at position 113. In the IL12A/Il12B heteromer there is an interchain disulphide bond between cysteine residues at positions 177 of the beta chain and 74 in the alpha chain. |