calmodulin   Click here for help

GtoPdb Ligand ID: 2351

Synonyms: Ca2+/calmodulin | Ca2+/CaM | calcium-calmodulin | CaM
Compound class: Endogenous peptide in human, mouse or rat
Comment: Consists of endogenous peptide calmodulin in complex with up to 4 calcium ions. The name 'calmodulin' is an abbreviation of 'calcium-modulated protein'.
Species: Human
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Ligand Activity Visualisation Charts

These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.

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View interactive charts of activity data across species
Peptide Sequence Click here for help
ADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTD
SEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK
Selected 3D Structures
PDB Id: 2Y4V
Image of ligand 3D structure from RCSB PDB
Post-translational Modification
Residue 1 is N-acetylalanine; residues 13, 21 and 94 are N6-acetyllysine; residues 99 and 138 are phosphotyrosine; residue 115 is N6,N6,N6-trimethyllysine; residue 44 is predicted to be phosphothreonine