Synonyms: compound F8 [PMID: 37145039]
Compound class:
Synthetic organic
Comment: This compound is selectively metabolised to the fluorescent product (4-OH F8) by cytochrome P450 3A4 (CYP3A4) [1]. It is not converted by other P450 isozymes, and its metabolism is inhibited by small molecules that are active against CYP3A/CYP3A4 but not other CYPs. F8 is proposed as a molecular tool for monitoring CYP3A4 activities in living cells and tissue preparations.
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Molecular structure representations generated using Open Babel