UH-AH 37   Click here for help

GtoPdb Ligand ID: 8583

Compound class: Synthetic organic
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2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 3
Topological polar surface area 58.1
Molecular weight 383.14
XLogP 4.23
No. Lipinski's rules broken 0
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Canonical SMILES CN1CCC(CC1)CC(=O)n1c2ccccc2c(=O)[nH]c2c1c(Cl)ccc2
Isomeric SMILES CN1CCC(CC1)CC(=O)n1c2ccccc2c(=O)[nH]c2c1c(Cl)ccc2
InChI InChI=1S/C21H22ClN3O2/c1-24-11-9-14(10-12-24)13-19(26)25-18-8-3-2-5-15(18)21(27)23-17-7-4-6-16(22)20(17)25/h2-8,14H,9-13H2,1H3,(H,23,27)
1. Gillberg PG, Sundquist S, Nilvebrant L. (1998)
Comparison of the in vitro and in vivo profiles of tolterodine with those of subtype-selective muscarinic receptor antagonists.
Eur J Pharmacol, 349 (2-3): 285-92. [PMID:9671109]
2. Wess J, Lambrecht G, Mutschler E, Brann MR, Dörje F. (1991)
Selectivity profile of the novel muscarinic antagonist UH-AH 37 determined by the use of cloned receptors and isolated tissue preparations.
Br J Pharmacol, 102 (1): 246-50. [PMID:2043926]