CXCL9   Click here for help

GtoPdb Ligand ID: 837

Synonyms: MIG | monokine induced by gamma-interferon
Immunopharmacology Ligand
Comment: CXCL9 is a chemokine. It acts as a chemoattractant for activated T cells and tumour-infiltrating leukocytes, but not for neutrophils or monocytes.
Species: Human
Click here for help
1. Heise CE, Pahuja A, Hudson SC, Mistry MS, Putnam AL, Gross MM, Gottlieb PA, Wade WS, Kiankarimi M, Schwarz D et al.. (2005)
Pharmacological characterization of CXC chemokine receptor 3 ligands and a small molecule antagonist.
J Pharmacol Exp Ther, 313 (3): 1263-71. [PMID:15761110]
2. O'Brien JC, Rainwater YB, Malviya N, Cyrus N, Auer-Hackenberg L, Hynan LS, Hosler GA, Jacobe HT. (2017)
Transcriptional and Cytokine Profiles Identify CXCL9 as a Biomarker of Disease Activity in Morphea.
J Invest Dermatol, 137 (8): 1663-1670. [PMID:28450066]
3. Weng Y, Siciliano SJ, Waldburger KE, Sirotina-Meisher A, Staruch MJ, Daugherty BL, Gould SL, Springer MS, DeMartino JA. (1998)
Binding and functional properties of recombinant and endogenous CXCR3 chemokine receptors.
J Biol Chem, 273 (29): 18288-91. [PMID:9660793]