CCL22   Click here for help

GtoPdb Ligand ID: 798

Synonyms: dc/β-ck | macrophage-derived chemokine | STCP1
Immunopharmacology Ligand
Comment: CCL22 is a CC family chemokine. It is one of the endogenous agonists for the chemokine receptor CCR4.
Species: Human
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1. Godiska R, Chantry D, Raport CJ, Sozzani S, Allavena P, Leviten D, Mantovani A, Gray PW. (1997)
Human macrophage-derived chemokine (MDC), a novel chemoattractant for monocytes, monocyte-derived dendritic cells, and natural killer cells.
J Exp Med, 185 (9): 1595-604. [PMID:9151897]
2. Imai T, Chantry D, Raport CJ, Wood CL, Nishimura M, Godiska R, Yoshie O, Gray PW. (1998)
Macrophage-derived chemokine is a functional ligand for the CC chemokine receptor 4.
J Biol Chem, 273 (3): 1764-8. [PMID:9430724]
3. Struyf S, Proost P, Sozzani S, Mantovani A, Wuyts A, De Clercq E, Schols D, Van Damme J. (1998)
Enhanced anti-HIV-1 activity and altered chemotactic potency of NH2-terminally processed macrophage-derived chemokine (MDC) imply an additional MDC receptor.
J Immunol, 161 (6): 2672-5. [PMID:9743322]
4. Vulcano M, Albanesi C, Stoppacciaro A, Bagnati R, D'Amico G, Struyf S, Transidico P, Bonecchi R, Del Prete A, Allavena P et al.. (2001)
Dendritic cells as a major source of macrophage-derived chemokine/CCL22 in vitro and in vivo.
Eur J Immunol, 31 (3): 812-22. [PMID:11241286]