Rac2   Click here for help

GtoPdb Ligand ID: 5251

Synonyms: p21-Rac2
Species: Human
References
1. Bae YS, Cantley LG, Chen CS, Kim SR, Kwon KS, Rhee SG. (1998)
Activation of phospholipase C-gamma by phosphatidylinositol 3,4,5-trisphosphate.
J Biol Chem, 273 (8): 4465-9. [PMID:9468499]
2. Camps M, Carozzi A, Schnabel P, Scheer A, Parker PJ, Gierschik P. (1992)
Isozyme-selective stimulation of phospholipase C-beta 2 by G protein beta gamma-subunits.
Nature, 360 (6405): 684-6. [PMID:1465133]
3. Illenberger D, Walliser C, Nurnberg B, Diaz Lorente M, Gierschik P. (2003)
Specificity and structural requirements of phospholipase C-beta stimulation by Rho GTPases versus G protein beta gamma dimers.
J Biol Chem, 278 (5): 3006-14. [PMID:12441352]
4. Illenberger D, Walliser C, Strobel J, Gutman O, Niv H, Gaidzik V, Kloog Y, Gierschik P, Henis YI. (2003)
Rac2 regulation of phospholipase C-beta 2 activity and mode of membrane interactions in intact cells.
J Biol Chem, 278 (10): 8645-52. [PMID:12509427]
5. Lee CH, Park D, Wu D, Rhee SG, Simon MI. (1992)
Members of the Gq alpha subunit gene family activate phospholipase C beta isozymes.
J Biol Chem, 267 (23): 16044-7. [PMID:1322889]
6. Park D, Jhon DY, Lee CW, Lee KH, Rhee SG. (1993)
Activation of phospholipase C isozymes by G protein beta gamma subunits.
J Biol Chem, 268 (7): 4573-6. [PMID:8383116]
7. Piechulek T, Rehlen T, Walliser C, Vatter P, Moepps B, Gierschik P. (2005)
Isozyme-specific stimulation of phospholipase C-gamma2 by Rac GTPases.
J Biol Chem, 280 (47): 38923-31. [PMID:16172125]
8. Walliser C, Retlich M, Harris R, Everett KL, Josephs MB, Vatter P, Esposito D, Driscoll PC, Katan M, Gierschik P et al.. (2008)
rac regulates its effector phospholipase Cgamma2 through interaction with a split pleckstrin homology domain.
J Biol Chem, 283 (44): 30351-62. [PMID:18728011]