Synonyms: BN-201 | BN201 | OCS-05
Compound class:
Synthetic organic
Comment: The chemical structure for privosegtor was obtained from proposed INN list 130 (Feb. 2024), in which the compound is described as a serum/ glucocorticoid-regulated kinase 2 (SGK2) activator. This is a structural match for clinical candidate OCS-05 (also known as BN201) that is being investigated as a neuroprotective therapy [2].
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References |
1. Villoslada P, Masso M, Paris S, Hutchings S, Koch A. (2023)
A Phase 1 randomized study on the safety and pharmacokinetics of OCS-05, a neuroprotective disease modifying treatment for Acute Optic Neuritis and Multiple Sclerosis. Sci Rep, 13 (1): 5099. [PMID:36991169] |
2. Villoslada P, Vila G, Colafrancesco V, Moreno B, Fernandez-Diez B, Vazquez R, Pertsovskaya I, Zubizarreta I, Pulido-Valdeolivas I, Messeguer J et al.. (2019)
Axonal and Myelin Neuroprotection by the Peptoid BN201 in Brain Inflammation. Neurotherapeutics, 16 (3): 808-827. [PMID:30815844] |