Synonyms: Example 26A [WO2014096388] | MEN1703 | SEL-24 | SEL24
Compound class:
Synthetic organic
Comment: The chemical structure for dapolsertib was obtained from proposed INN list 130 (Feb. 2024). This matched to clinical lead SEL-24 (MEN1703) via PubChem, and to compound 26A in patent WO2014096388 [1]. The compound is proposed as dual pan-PIM/FLT3 kinase inhibitor for the treatment of acute myeloid leukemia.
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References |
1. Czardybon W, Brzózka K, Galezowski M, Windak R, Milik M, Zawadzka M, Guzik E, Prokop M, Wilik K, Sabiniarz A et al.. (2014)
Novel benzimidazole derivatives as kinase inhibitors. Patent number: WO2014096388A2. Assignee: Selvita S.A.. Priority date: 20/12/2013. Publication date: 26/06/2014. |