Synonyms: Gantrisin® | NU-445 | sulfafurazole | sulphafurazole
sulfisoxazole is an approved drug (FDA (1948))
Compound class:
Synthetic organic
Comment: Sulfisoxazole (sulfafurazole) is a sulfonamide antibacterial compound [4-5].
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References |
1. Achari A, Somers DO, Champness JN, Bryant PK, Rosemond J, Stammers DK. (1997)
Crystal structure of the anti-bacterial sulfonamide drug target dihydropteroate synthase. Nat Struct Biol, 4 (6): 490-7. [PMID:9187658] |
2. Bermingham A, Derrick JP. (2002)
The folic acid biosynthesis pathway in bacteria: evaluation of potential for antibacterial drug discovery. Bioessays, 24 (7): 637-48. [PMID:12111724] |
3. Ovung A, Bhattacharyya J. (2021)
Sulfonamide drugs: structure, antibacterial property, toxicity, and biophysical interactions. Biophys Rev, 13 (2): 259-272. [PMID:33936318] |
4. SARNOFF SJ, FREEDMAN MA, HYMAN AA. (1946)
The treatment of Bacillus proteus infections with NU-445. J Urol, 55: 417-27. [PMID:21020389] |
5. STEWART BL, LASH JJ. (1950)
The clinical use of NU-445 (gantrisin) in the treatment of urinary tract infections; a report of 100 cases. J Urol, 64 (6): 801-10. [PMID:14795570] |