Synonyms: 5'-deoxy-5'-thiothymidine | 5'-Thiothymidine
Compound class:
Synthetic organic
Comment: FUZS-5 is a thymidine nucleoside analogue. It has been found to interact with an allosteric site on the SARS-CoV-2 Nsp15 endoribonuclease [1].
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References |
1. Godoy AS, Nakamura AM, Douangamath A, Song Y, Noske GD, Gawriljuk VO, Fernandes RS, Pereira HDM, Oliveira KIZ, Fearon D et al.. (2023)
Allosteric regulation and crystallographic fragment screening of SARS-CoV-2 NSP15 endoribonuclease. Nucleic Acids Res, 51 (10): 5255-5270. DOI: 10.1101/2022.09.26.509485 [PMID:37115000] |