Synonyms: HAPA-B | Sch 21420
isepamicin is an approved drug
Compound class:
Synthetic organic
Comment: Isepamicin is a semisynthetic derivative of gentamicin B, with activity against Gram-negative bacteria [2]. It belongs to the aminoglycoside class of antibacterial compounds.
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References |
1. Kabins SA, Nathan C. (1978)
In vitro activity of Sch 21420, derivative of gentamicin B, compared to that of amikacin. Antimicrob Agents Chemother, 14 (5): 786-7. [PMID:727766] |
2. Nagabhushan TL, Cooper AB, Tsai H, Daniels PJ, Miller GH. (1978)
The syntheses and biological properties of 1-N-(S-4-amino-2-hydroxybutyryl)-gentamicin B and 1-N-(S-3-amino-2-hydroxypropionyl)-gentamicin B. J Antibiot (Tokyo), 31 (7): 681-7. [PMID:690003] |
3. Yu PK, Washington 2nd JA. (1978)
In vitro evaluation of a semisynthetic derivative of gentamicin B (Sch 21420). Antimicrob Agents Chemother, 13 (5): 891-2. [PMID:666309] |